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GMP Biotech Product

GUANIDINE THIOCYANATE BIOTECH

GMP
Product Code: GTHI-4221

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Price per unit (USD) Price per kilogram (USD)
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QUANTITY
Product Code: GTHI-4221
Suitable for use in biological and biotech chemical process applications from R&D through scale cGMP production.

This is a high purity, reagent grade product, purified under cGMP conditions. Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more efficiently than Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.

Formula: C2H6N4S
F.W.: 118.16 g/mol
CAS #: 593-84-0

Product Specifications

ANALYSIS SPECIFICATIONS
Absorbance (1.7M)

280 nm

300 nm

340 nm

< = 0.300 a.u.

< = 0.050 a.u.

< = 0.030 a.u.

Appearance and Color

 

White Crystals

Assay, Dried Basis 

 

99.0 - 101.0%

Enzymes

DNase

Protease

RNase

None Detected

None Detected

None Detected

Identification, IR  
Conforms to Reference Standard
Loss on Drying  
< = 0.5%
Melting Range 115-121°C
pH (5%)  
5.0 - 7.0
Sulfated Ash  
< = 0.5%
Sulfate  
< = 50 ppm
Trace Metals

Arsenic (As)

Aluminum (Al)

Barium (Ba)

Bismuth (Bi)

Calcium (Ca)

Cadmium (Cd)

Chromium (Cr)

Cobalt (Co)

Copper (Cu)

Iron (Fe)

Potassium (K)

Lead (Pb)

Lithium (Li)

Magnesium (Mg)

Manganese (Mn)

Molybdenum (Mo)

Sodium (Na)

Nickel (Ni)

Strontium (Sr)

Zinc (Zn)

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 10 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 50 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5000 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

 

Printable Version

Key Product Features:

  • Appears as a white crystalline product
  • Manufactured in accordance with IPEC
  • Manufactured in an enzyme free, hormone free and animal free environment
  • Contains no known major food allergens (as defined by FDA and WHO)
  • The final product nor its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
  • Is not subject to genetic modification
  • Synonyms: Guanidine Isothiocyanate

Shelf Life Policy:

Unless otherwise noted on the Shelf-Life Statement and CoA, this product has a 2-year retest date supported by a 3-year ICH Q1 Stability Study (if one is completed).

Storage & Shipping:

Refer to SDS.

Package Sizes:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.